Thyroid Imbalance

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THYROID IMBALANCE

thyroid imbalance

It is known that people affected by thyroid imbalance, specifically hypothyroidism, are not aware of their condition in the early days even though they may be experiencing symptoms included in the list below.

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Symptoms associated with hypothyroidism:

  • Weight gain
  • Cold and heat intolerance
  • Fatigue
  • Decreased metabolic rate
  • Impairment of memory
  • Odema or Fluid retention
  • Swelling of neck
  • Constipation
  • Drynes of hair and skin
  • Depression
  • Low sexual desire
  • Headaches, Migraines
  • Irregular menstrual cycles
  • Lack of concentration
  • Pre menstrual syndrome
  • Tongue enlargement
  • Deep voice
  • Infertility
  • Low blood sugar levels
  • High Cholesterol
  • High Triglyceride levels

In the body, Thyroid Hormone is present as two major forms:

(T3) Triiodothyronine – T3 is the active from of thyroid hormone, with the thyroid gland producing 20 % while numerous other tissues in the body produce the rest by converting T4 to T3.

(T4) Thyroxine – T4 is the inactive form of thyroid hormone and is produced by the thyroid gland.

Imbalances in thyroid hormone levels can be efficiently treated with thyroid replacement therapy. It must be carefully titrated to the patient. Although there are many commercially available thyroid medications on the market, it has been observed that not all patients respond to thyroid therapy in a similar manner. Several factors may contribute to the inadequate response to commercially available therapies for thyroid imbalance. These include:

  • Use of inappropriate dose strength
  • Bioavailability of appropriate dosage form
  • Non-equivalence between the brand and generic therapy options
  • Batch variability between dosages
  • Pharmacodynamic variability or different response to the active
  • ingredient, dependent on age and other factors such as race and gender.
  • Sensitivity of patients towards excipients and other additives in the medication.

Use of compounded thyroid medications has several advantages as it allows:

  • Formulation of strengths in T3 and T4 combinations that are commercially not available
  • Creation of dosages with accuracy to minimize variability.
  • Possibility to compound thyroid medications when commercial availability is low
  • Ability to provide formulations as sustained-release thyroid preparations
  • Possibility to eliminate excipients or additives that trigger adverse reactions in the patient (for example, possibility to formulate dye-free Thyroid hormone preparations).

How does compounding work?

Compounding pharmacies can produce unique dosage forms based on patient preferences and/or restrictions. Examples include dye-free, preservative-free, alcohol-free, and/or sugar-free forms of medications.

Many compounds are specialized medication combinations or liquid or cream forms of products that are not otherwise commercially available.

Frequently Asked Questions

What is Compounding?

In general, compounding is a practice in which a licensed pharmacist, upon a physicians’ prescription order, combines, mixes, or alters ingredients of a drug to create a medication tailored to the needs of an individual patient.

A health care provider will prescribe a compounded drug when commercially available products do not meet your needs. Preparing a paste or suspension from crushed tablets is one example of compounding. Likewise, adding flavoring to medication is also compounding.

Is a prescription required?

Yes, a prescription order from a physician is required for the pharmacist to compound your medication to meet your specific needs.

Are compounded prescriptions covered by insurance?

Some health insurance plans cover compounded medications. Check with your insurance company to see if you have coverage. Many pharmacies are able to bill insurance companies directly for compounded medications. If unable to bill your insurance company, you may submit a claim form to your insurance company to reimburse you directly. Depending on the nature of the product, these medications may be just as affordable as your conventional prescriptions.

How does my medical provider play a role in compounding?

Many medical providers are aware of the practice of compounding, and they may work with your local compounding pharmacy to provide the right medication for you. Talk to your pharmacist or doctor today if you feel that a compounded prescription may be a better way to manage a health condition for you or your family member.

Does a compounding pharmacist have special training?

All pharmacists are taught in pharmacy school how to properly compound medications, and many compounding pharmacists have advanced training after pharmacy school graduation. Compounding pharmacists utilize their unique pharmacy skills, knowledge, and creativity to work with you and your prescriber to prepare medication in a dosage form that has been customized to your particular needs.

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